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Well, of course, for the treatment of acne require special medication. There are many expensive cosmetics, the use of which reduces inflammation, but this approach gives only a short-term effect. There is one great tool ” Retinoic ointment “, which effectively treats and attack the causes of acne. No chance for acne to Of course, tretinoin cream 0.25 is primarily intended for the treatment of acne ! In 13 -cis – cream, which is part of retinoic ointment has two important properties which are almost not used in the treatment of acne. Use it is very simple : you need to apply a thin layer of cream on cleansed skin 1-2 times a day. But for a long time on many websites there are discussions about the rejuvenation of the skin with it. First – penetrating deep into the skin, it rearranges fibroblasts cells that produce collagen, elastic fibers, and the substance that fills the space there between. 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