Contents: What is prednisone and why is it prescribed? Weight gain and other side effects of this medication… 10 Things you should know/do before taking prednisone How should it be used? In conclusion: The benefits and the risks weighed The main benefit of prednisone is that it is a corticosteroid medication that is very effective in decreasing inflammation. Some common names of other corticosteroids like prednisone that might be more recognizable are cortisone and hydrocortisone. These medications have great potential in treating several conditions such as lupus skin rashes, skin rashes from other conditions, rheumatoid arthritis, asthma, and lupus. Corticosteroids mimic the cortisol action that is naturally produced in the body by the adrenal glands (these glands are located right on the top of the kidneys). Corticosteroids suppress your immune system, which can help control conditions like lupus, in which your immune system mistakenly attacks its own tissues. Prednisone is a glucocorticoid (chemicals that can stop inflammation) and plays an important role in regulating the functioning of the entire body. xanax or ativan Day 1: 10 mg PO before breakfast, 5 mg after lunch and after dinner, and 10 mg at bedtime Day 2: 5 mg PO before breakfast, after lunch, and after dinner and 10 mg at bedtime Day 3: 5 mg PO before breakfast, after lunch, after dinner, and at bedtime Day 4: 5 mg PO before breakfast, after lunch, and at bedtime Day 5: 5 mg PO before breakfast and at bedtime Day 6: 5 mg PO before breakfast Immediate-release: ≤10 mg/day PO added to disease-modifying antirheumatic drugs (DMARDs) Delayed-release: 5 mg/day PO initially; maintenance: lowest dosage that maintains clinical response; may be taken at bedtime to decrease morning stiffness with rheumatoid arthritis Take with meal or snack High-dose glucocorticoids may cause insomnia; immediate-release formulation is typically administered in morning to coincide with circadian rhythm Delayed-release formulation takes about 4 hours to release active substances; thus, with this formulation, timing of dose should take into account delayed-release pharmacokinetics and disease or condition being treated (eg, may be taken at bedtime to decrease morning stiffness with rheumatoid arthritis) Allergic: Anaphylaxis, angioedema Cardiovascular: Bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, hypertension, hypertrophic cardiomyopathy in premature infants, myocardial rupture after recent myocardial infarction, pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis, vasculitis Dermatologic: Acne, allergic dermatitis, cutaneous and subcutaneous atrophy, dry scalp, edema, facial erythema, hyper- or hypopigmentation, impaired wound healing, increased sweating, petechiae and ecchymoses, rash, sterile abscess, striae, suppressed reactions to skin tests, thin fragile skin, thinning scalp hair, urticaria Endocrine: Abnormal fat deposits, decreased carbohydrate tolerance, development of cushingoid state, hirsutism, manifestations of latent diabetes mellitus and increased requirements for insulin or oral hypoglycemic agents in diabetics, menstrual irregularities, moon facies, secondary adrenocortical and pituitary unresponsiveness (particularly in times of stress, as in trauma, surgery, or illness), suppression of growth in children Fluid and electrolyte disturbances: Fluid retention, potassium loss, hypertension, hypokalemic alkalosis, sodium retention Gastrointestinal: Abdominal distention, elevation of serum liver enzymes levels (usually reversible upon discontinuance), hepatomegaly, hiccups, malaise, nausea, pancreatitis, peptic ulcer with possible perforation and hemorrhage, ulcerative esophagitis General: Increased appetite and weight gain Metabolic: Negative nitrogen balance due to protein catabolism Musculoskeletal: Osteonecrosis of femoral and humeral heads, Charcot-like arthropathy, loss of muscle mass, muscle weakness, osteoporosis, pathologic fracture of long bones, steroid myopathy, tendon rupture, vertebral compression fractures Neurologic: Arachnoiditis, convulsions, depression, emotional instability, euphoria, headache, increased intracranial pressure with papilledema (pseudotumor cerebri; usually following discontinuance of treatment), insomnia, meningitis, mood swings, neuritis, neuropathy, paraparesis/paraplegia, paresthesia, personality changes, sensory disturbances, vertigo Ophthalmic: Exophthalmos, glaucoma, increased intraocular pressure, posterior subcapsular cataracts, central serous chorioretinopathy Reproductive: Alteration in motility and number of spermatozoa Untreated serious infections Documented hypersensitivity Varicella Administration of live or attenuated live vaccine (Advisory Committee on Immunization Practices (ACIP) and American Academy of Family Physicians (AAFP) state that administration of live virus vaccines usually is not contraindicated in patients receiving corticosteroid therapy as short-term ( Monitor for hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing syndrome, and hyperglycemia Prolonged use associated with increased risk of infection; monitor Use with caution in cirrhosis, ocular herpes simplex, hypertension, diverticulitis, hypothyroidism, myasthenia gravis, peptic ulcer disease, osteoporosis, ulcerative colitis, psychotic tendencies, renal insufficiency, pregnancy, diabetes mellitus, congestive heart failure, thromboembolic disorders, GI disorders Long-term treatment associated with increased risk of osteoporosis, myopathy, delayed wound healing Patients receiving corticosteroids should avoid chickenpox or measles-infected persons if unvaccinated Latent tuberculosis may be reactivated (patients with positive tuberculin test should be monitored) Some suggestion (not fully substantiated) of slightly increased cleft palate risk if corticosteroids are used in pregnancy Methylprednisolone is preferred in hepatic impairment because prednisone must be converted to prednisolone in liver Prolonged corticosteroid use may result in elevated intraocular pressure, glaucoma, or cataracts May cause impairment of mineralocorticoid secretion; administer mineralocorticoid concomitantly May cause psychiatric disturbances; monitor for behavioral and mood changes; may exacerbate pre-existing psychiatric conditions Monitor for Kaposi sarcoma Pregnancy category: C (immediate release); D (delayed release) Drug may cause fetal harm and decreased birth weight; maternal corticosteroid use during first trimester increases incidence of cleft lip with or without cleft palate Lactation: Of maternal serum metabolites, 5-25% are found in breast milk; not recommended, or, if benefit outweighs risk, use lowest dose Glucocorticosteroid; elicits mild mineralocorticoid activity and moderate anti-inflammatory effects; controls or prevents inflammation by controlling rate of protein synthesis, suppressing migration of polymorphonuclear leukocytes (PMNs) and fibroblasts, reversing capillary permeability, and stabilizing lysosomes at cellular level; in physiologic doses, corticosteroids are administered to replace deficient endogenous hormones; in larger (pharmacologic) doses, they decrease inflammation The above information is provided for general informational and educational purposes only. 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Medindia's drug directory has currently 19 Brands of Prednisone listed. New generics and brands are constantly being updated as and when they are approved by drug controller and available in the pharmacies. India is the world's capital for quality medicines, be it pharmaceutical formulations, herbal medicines or nutraceuticals. Our Pharma Division deals only with the best, GMP certified generics and branded medication for the export market. Prednisone is also used to treat children with juvenile rheumatoid arthritis (JRA), acute leukemia, congenital adrenal hyperplasia, adrenocortical insufficiency, and nephrotic syndrome. It is also indicated for a variety of other endocrine, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and nervous system disorders. There is confusion between prednisone and the anabolic steroids used by bodybuilders. But, after the discovery of antibiotics, prednisone may be one of the more important types of medicines ever discovered. The most common side effects of taking prednisone include muscle weakness, osteoporosis, fractures, Cushing's syndrome, pituitary-adrenal axis suppression, growth suppression, glucose intolerance, acne, edema, hypertension, hypokalemia, alkalosis, cataracts, glaucoma, peptic ulcer, nausea, vomiting, headache, vertigo, seizures, psychoses, pseudotumor cerebri, and skin atrophy. Some kids also develop mood swings, become irritable, and have trouble sleeping when they take prednisone. Most side effects, especially growth suppression, edema, and immune system problems are going to be worse with long-term use of prednisone and less likely with the short term course that most children take for typical asthma attacks or for relief from poison ivy, etc. Although one of the more useful medicines in pediatrics, especially when you see the dramatic effects prednisone has on a child with a severe asthma attack, steroids can have serious side effects when overused or misused and they should only be prescribed when it is really necessary. Prednisone other names Prednisone and Other Steroids for Kids - Verywell Health, Prednisone Trade Name India Bonus Free Pills! - Builders Warehouse Xanax nausea Sertraline or prozac Where can you buy viagra Cytotec sublingual Canadian pharmacies that accept credit cards Uses generic names in all descriptions of drugs. Deltasone is the trade name for prednisone. Liquid pred and meticorten and orasone are other. 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