I know minocycline is an antibiotic related to doxycycline, yet I looked plaquenil up and found that it is a DMARD, used to treat malaria, rheumatoid arthritis and lupus. Plaquenil can change the intracellular PH and make antibiotics more effective. It works especially well with macrolide antibiotics. I wasn’t reacting well on the combination (too hard on my digestive system, severe herxing - but I have to add that I don't know which abx caused the problems), but most of my dr’s patients react very well. I found no connection to treating Lyme except that when used in combination with minocycline is affective at treating Lyme arthritis, and is fools insurance companies into thinking arthritis is exactly what is being treated. It's very common for LLMD's to use Plaquenil in all kinds of protocols. It can cause eye problems (I didn’t have them, but I had to stop this combination after 6 weeks). Hydroxychloroquine overdose Hydroxychloroquine narcotic Chloroquine overdose death Plaquenil back pain and headache Azithromycin. In combination, these antibiotics have been found to be useful in reversing PDD in children born with Lyme disease and very early onset Lyme disease. Hydroxychloroquine can be used in treatment for one who has a Lyme induced autoimmune reaction. Hydroxychloroquine Drugs with low anti-Bart activity include Doxy and Biaxin even though these drugs are thought to be only Lyme drugs. Minocycline is a little more active against Bart. Zithromax orally is a poor Lyme drug and has mild anti-Bart effects. Rifampin is somewhat more active against Bart. If Zithromax azithromycin is used orally to treat Lyme disease, it is ineffective unless it is used with a "cyst-buster" such as Flagyl metronidazole or Plaquenil hydroxychloroquine. Check out Dr. Burrascano's treatment guidelines, starting on Page 14, regarding the different antibiotics used to treat Lyme disease. We should always watch for side effects that can be damaging!! Yet, of the millions of symptoms Lyme has caused me, arthritis isn't one. My pharmacist (and the dr also afterwards) advised me to get my eyes checked before starting treatment, so that my dr would know for sure where the damage comes from, if I had any showing up. Lyme combination azithromycin doxycycline hydroxychloroquine Randomized Trial of Longer-Term Therapy for Symptoms., LymeMD Lyme 2010 A brief update What does a plaquenil rash look likeLong term plaquenil therapyPlaquenil eye exam costBuy malaria pills online hydroxychloroquineHydroxychloroquine 200 mg tab coupon In addition to doxycycline and beta-lactams, some clinical drugs such as vancomycin, ofloxacin, clarithromycin, and hydroxychloroquine, which are not recommended for treating Lyme disease, also exhibited some weak activity on the 10 day old stationary phase B. burgdorferi culture, either alone or in combination with doxycycline and cefoperazone. Drug Combinations against Borrelia burgdorferi Persisters.. Zithromax Z-Pak - can it be used for lymes disease treatment?. LymeMD Plaquenil alone?. Research by Zhang et al. seems to indicate a good combination for eradicating spirochetes and persister cells as well as dissolving biofilms at least in vitro is Doxycycline Cefuroxime Ceftin Oil of Oregano If one had Babesia as well, I’m wondering if it would be too much to add azithromycin Zithromax and atovaquone Mepron to this regimen. In this 3-arm study, entitled Persistent Lyme Empiric Antibiotic Study Europe PLEASE, ceftriaxone followed by doxycycline arm 1 or ceftriaxone followed by the combination of clarithromycin and hydroxychloroquine arm 2 are compared to short-term therapy with ceftriaxone followed by placebo arm 3. Here, we describe the study protocol. The first-line standard of care treatment for adults with Lyme disease is doxycycline, a tetracycline antibiotic. Other antibiotics that have activity against borrelia include the penicillin-like antibiotic, amoxicillin, and the cephalosporin, Ceftin. The mainstay of treatment is with oral pill antibiotics.