In general, it's important to mention this to your prescriber. Hydroxychloroquine (Plaquenil and generics) can itself cause fatigue in some users, it can interrupt sleep patterns (especially by causing more vivid dreams) which in turn makes one more tired. Can you take lyrica with plaquenil Lupus weight gain plaquenil Chloroquine and ambien Chloroquine resistance blood stage inhibition Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Check with your doctor as soon as possible if any of the following side effects occur blurred vision or any change in vision – this effect may also occur or worsen after stopping. change in colour of hair or skin pigment. flu-like symptoms sudden lack of energy, fever, cough, sore throat. Is anyone taking Plaquenil and if so, do you find it works for fatigue. Should I just bite the bullet and give it a whirl. I should mention that I believe many of my aches and pain is related to the fact that I am obese especially in hips/knees. I imagine this plays a part in how tired I am at times. This is especially true in those individuals with G6PD deficiency. The drug can also lower blood counts (red cell, white cells and others too) which in turn can cause fatigue. Plaquenil fatigue Plaquenil for CFS. ProHealth Fibromyalgia, ME/CFS and., Plaquenil - Uses, Side Effects, Interactions - Saliva drug test rx hydroxychloroquine false positive drug test Medication side effects Several medications used to treat RA can cause fatigue as a side effect, including Methotrexate Rheumatrex, Trexall, Otrexup. Hydroxychloroquine Plaquenil. Oral NSAIDs. Medications used to treat conditions such as high cholesterol, high blood pressure, and diabetes. How Rheumatoid Arthritis Triggers Chronic Fatigue. Treatment/Plaquenil -. Things that Changed My Life with Lupus Fatigue, Part 3. May 23, 2016 Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Either that or maybe I am developing FM as well.anyhow, the plaquenil has helped my joint pain but after 6 months I have more fatigue, muscle pain and overall discomfort than I did before. For the past month I haven't been able to hold my arms over my head for more than a few seconds due to the pain. Feb 19, 2020 Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss.