Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Rheumatoid factor dropped plaquenil Hydroxychloroquine gh Hydroxychloroquine and azithromycin Plaquenil dosage by weight Serious skin reactions can occur during treatment with this medicine. Check with your doctor right away if you or your child have any of the following symptoms while using this medicine blistering, peeling, or loose skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine. Sir, Hydroxychloroquine is widely used in the treatment of rheumatoid arthritis and systemic lupus erythematosus, with very few reported side‐effects. We report the case of a 65‐yr‐old woman who developed Stevens–Johnson syndrome 2 weeks after commencing treatment with hydroxychloroquine. Other cutaneous adverse reactions of hydroxychloroquine have also been reported Table-1 11–16, 22. Two out of the seven reported cases of hydroxychloroquine induced cutaneous adverse reactions were fatal. In our case, the patient’s skin lesions resolved with high dose and slow taper course of steroid treatment. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine skin rash treatment Hydroxychloroquine Sulfate Rash Reports - DrugInformer, Stevens–Johnson syndrome in association with. Chloroquine malaria pills Hydroxychloroquine is an antimalarial medication that can cause hyperpigmentation of nails, mucosa, and skin 1–5. Retrospective studies cite the incidence of drug-related hyperpigmentation from hydroxychloroquine to be as high as 33% of individuals. Elder abuse is a cause of significant morbidity and mortality in older individuals 7–9. Hydroxychloroquine-Associated Hyperpigmentation Mimicking.. Hydroxychloroquine-induced erythema multiforme. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Mar 17, 2019 An overdose of hydroxychloroquine can be fatal, especially in children. Take hydroxychloroquine for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. When treating lupus or arthritis, tell your doctor if your symptoms do not improve after 6 months of treatment. Hydroxychloroquine is used to treat rheumatoid arthritis; discoid and systemic lupus erythematosus SLE. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. If you have lupus, it may also improve the rash. It may be as long as 12 weeks before you notice the benefits. Background Hydroxychloroquine sulfate and other antimalarial drugs have been used successfully as adjunctive therapy for patients with cutaneous lesions of dermatomyositis over the past 20 years. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis.