Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine 200mg twice a day Can plaquenil cause extreme fatigue Side effects of plaquenil withdrawal Chloroquine synthesis mechanism Uses of Chloroquine It is used to treat or prevent malaria. It is used to treat a type of bowel infection. It may be given to you for other reasons. Radiosensitization by chloroquine appears to be a result of the promotion of both apoptosis and necrosis Online Resource 3 S8–S9. Moreover, these findings indicate the existence of both cytoprotective and cytotoxic functions of autophagy in response to radiation in the same experimental system. Chloroquine is an established antimalarial agent that has been recently tested in clinical trials for its anticancer activity. The favorable effect of chloroquine appears to be due to its ability to sensitize cancerous cells to chemotherapy, radiation therapy, and induce apoptosis. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Chloroquine cytotoxic UpToDate, A switch between cytoprotective and cytotoxic autophagy in. Hydroxychloroquine and neutropenia Corresponding to 400 mg of hydroxychloroquine as adopted in the Singapore study. Chloroquine/hydroxychloroquine might thus be a valuable option to be tested in low-cost antiretroviral combinations, but correct dosages should be used, considering that the study participants should be regularly monitored to prevent retinopathy. New insights into the antiviral effects of chloroquine - The.. Chloroquine Is a Zinc Ionophore - PubMed Central PMC. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. The cytotoxic activities of chemotherapeutic agents are usually associated with increased production of ROS. Animals treated with chloroquine alone did not show any significant alteration in the levels of reduced glutathione GSH and lipid peroxides and catalase and glutathione peroxidase activities as compared to the control group. Chloroquine, a widely-used anti-malarial and autoimmune disease drug, has recently been reported as a potential broad-spectrum antiviral drug. 8,9 Chloroquine is known to block virus infection by.