For the last seven months I have been on Prednisone up to 60 mg a day and Imuran 150 mg a day. Needless to say not only did neither drug work to bring my platelets up or suppress my Lupus, I suffered with every side effect almost in the book. Does plaquenil affect immune system Is there weight loss with plaquenil Hydroxy chloroquine rheumatoid arthritis pregnancy Plaquenil and Thrombocytopenia - from FDA reports Summary Thrombocytopenia is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have High blood pressure. My mother had many many health issues. Including kidney failure and low platelets. When mom struggled with low platelets, we did not know she had lupus. She went through the bone marrow testing, etc. They did steroids for a long time to keep them up as well. What we found out was her spleen was eating up her platelets. On occasion, as an autoimmune disease, RA can turn its immune defenses on itself and destroy the blood-clotting cells, leading a low platelet count known as thrombocytopenia. Thrombocytopenia is also commonly caused by the drugs used to treat RA. My hematologist also was very wary of the side effects and I am now off the Imuran and my Prednisone is down to 15 mg a day with less of the drug side effects. My first RA and I parted ways in July after he kept wanting to increase the doses of the medications even though I was getting high liver enzyme and bilirubin levels due to the drugs. Plaquenil lowef platelets Are There Vitamins That Can Raise Platelets?, Kidney Biopsy/Low Platelets" Lupus Community - Support Group Plaquenil weightPlaquenil lymeChloroquine over the counterDistribution of malaria and chloroquine-resistantChloroquine malaria in wwii Aspirin and low platelet count plaquenal Voltaren and Cataflam purpose for hydrochlorot Are there dangers of smoking pot with low blood platelese? solumedrol acne Right clavical/clavicular sternal swelling + Tietze's Syndrome mtx blood level metal mouth Would this cause my platelet levels to drop below normal? Heard that penicillamine could cause SLE. Platelets plaquenil Anti-Inflammatories discussions.. How Rheumatoid Arthritis Affects Platelets. Low platelet count thrombocytopenia Causes, treatment, and.. I have been on Plaquenil for around 7 years and haven't been anemic during that time, not every person gets every side effect. Your low C3 and C4 means your immune system is very active it is using up all your complement, thus the low levels. You may be producing antibodies against your RBC's, WBC's and/or platelets. Platelet count increased is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Flagyl, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects.