It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil nervous system Is nausea and flu like symptoms normal when taking plaquenil If a child takes chloroquine by accident, get medical help right away. If you are 65 or older, use chloroquine with care. You could have more side effects. Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using chloroquine while you are pregnant. Preventing malaria Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and chloroquine in the treatment of rheumatoid arthritis RA, systemic lupus erythematosus SLE and other. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Effect of chloroquine on sle Chloroquine - Wikipedia, Mechanisms of action of hydroxychloroquine and chloroquine. What does plaquenil do for sjogren& 39Osteoarthritis joint nodules hydroxychloroquine Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine is an antimalarial drug that exhibits immune-modulatory properties in addition to antithrombotic and lipid-and glucose-lowering properties. 49 Hydroxychloroquine is mainly indicated for skin, joint, and serosal manifestations of SLE and has a glucocorticoid-sparing effect. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Antimalarial drugs, namely hydroxychloroquine HCQ in North America and Western Europe, remain the first line of treatment for SLE because they exert beneficial hematological and immunological effects which translate to efficacy in preventing flares, treating cutaneous and musculoskeletal lupus, retarding the onset of damage in general, and damage in the cutaneous and renal systems, preventing some cardiovascular and central nervous system complications and improving survival in SLE.