It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil cumulative dose toxicity Plaquenil side effects nausea Aug 30, 2011 A cumulative dose of 1000g of hydroxychloroquine or 460g of chloroquine was likely the largest risk factor, which was typically achieved after 5-7 years of a typical dosage 8, 10. However, there have been case reports of patients with hydroxychloroquine toxicity as early as 1.9 months after starting treatment 11. The normal dose of Plaquenil is 1 tablet a day 200mg/day. Some doctors recommend 2 a day 400mg/day but we find that 1 a day suits most people – the dose can always be increased for a flare. One of the attractions of this medication is its long ‘half-life’ – it stays in the system for days & weeks. For children and infants, the dose is based on weight. Usually, 5 mg per kg of body weight about 2.3 mg per pound once weekly is recommended, not to exceed the normal adult dosage. Plaquenil comes only in adult-strength tablets, which taste extremely bitter when crushed or chewed. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Normal dosage for plaquenil Hydroxychloroquine Plaquenil Toxicity and., Plaqunil rash - Plaquenil hyperpigmentationPlaquenil biologicPlaquenil nursing interventionsWhat does plaquenil do to the bodyHydroxychloroquine sulfate vs sodium bicarbonate Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart. Chloroquine Dosage Guide with Precautions -. Plaquenil Dosage - eMedTV Health Information Brought To Life. Hydroxychloroquine Side Effects, Dosage, Uses, and More. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Dosage Plaquenil comes in 200 milligram mg tablets that are taken by mouth. To prevent malaria in adults, two tablets are typically taken once a week, on the same day each week.