While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Hi, I was diagnosed with RA and was put on sulfa, my rheumy tried adding mtx but i had awful side effects so am now on hydroxychloroquine and sulfa..this combination worked for anyone? Hi I've been on this combination for a few months and unfortunately it hasn't worked for me - but that's not to say it won't for you, we are all different in how we react to drugs. Sulphasalasine was helpful in my case but took 12 weeks to kick in. Coding eye exam for plaquenil Sulfa in plaquenil Reviews and ratings for sulfasalazine when used in the treatment of rheumatoid arthritis. 51 reviews submitted. User Reviews for Sulfasalazine to treat Rheumatoid Arthritis. "I started taking sulfasalazine SZS with Plaquenil 2 months ago for RA. Immediately felt dizzy, confused, nosebleed and depression and also severe vision changes. This article primarily covers the author's experience with the use of the combination of methotrexate MTX, sulfasalazine SSZ, and hydroxychloroquine HCQ to treat patients with rheumatoid arthritis RA. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. I'm about to start MTX & am hoping that I wont have side effects with that! The side effects of the methotrexate for me were horrendous (chronic chest infections) and I'm now asthmatic as a result. I've stopped Sulfa as I was experiencing a bad taste & smell, which may be caused by sulfa. After a while it wasn't as effective and I too was prescribed methotrexate alongside. Sulfasalazine and hydroxychloroquine rheumatoid arthritis Sulfasalazine and Plaquenil drug interactions - eHealthMe, TRIPLE THERAPY WITH METHOTREXATE, SULFASALAZINE, AND. Plaquenil hydroxychloraquineHydroxychloroquine loss of appetite Sulfasalazine works by slowing the radiographic progression damage to the joints of rheumatoid arthritis, and reducing pain and swelling. It is one of the first line treatments for moderate to severe rheumatoid arthritis, along with methotrexate and leuflunomide arava. Sulfasalazine - Medications for Rheumatoid Arthritis RA. Hydroxychloroquine Plaquenil. Sulfasalazine Azulfidine. O'Dell JR, Leff R, Paulsen G, et al. Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications results of a two-year, randomized, double-blind, placebo-controlled trial. Sulfasalazine oral tablet is a prescription medication that's used to treat rheumatoid arthritis, juvenile rheumatoid arthritis, and ulcerative colitis. Combination hydroxychloroquine and sulfasalazine - does it work for any of you. Now adding sulfasalazine hydroxychloroquine. Content on HealthUnlocked does.