This information should not take the place of medical care and advice from your healthcare providers. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus. Plaquenil dosage for lyme disease Hydroxychloroquine sickle cell dose Use of this drug during pregnancy should be avoided except in the suppression or treatment of malaria. -This drug crosses the placenta. -Therapeutic doses of 4-aminoquinolines have been associated with central nervous system damage, including ototoxicity auditory and vestibular toxicity, congenital deafness, retinal hemorrhages and abnormal retinal pigmentation. Pregnancy Hydroxychloroquine crosses the placenta. Data are limited regarding the use of PLAQUENIL during pregnancy. PLAQUENIL should be avoided in pregnancy. It should be noted that the 4-aminoquinolines in therapeutic doses have been associated with central nervous system damage, May 13, 2009 Other studies have reported that HCQ is safe to use during pregnancy but had no control group 35-40. All 4 of the studies 27-30 assessed the presence of congenital defects in babies born to women with autoimmune diseases Additional file 1, Table S2 and Figure Figure2a. 2a. For more information on rheumatoid arthritis or lupus in pregnancy please see the Mother To Baby fact sheet on those topics at: https://mothertobaby.org/fact-sheets/rheumatoid-arthritis/pdf or https://mothertobaby.org/fact-sheets/lupus-pregnancy/pdf/. Hydroxychloroquine is sold under several brand names, including Plaquenil®. Plaquenil use during pregnancy Plaquenil and Pregnancy - Antibiotics Home Page, Plaquenil Hydroxychloroquine Sulfate - Sanofi Hydroxychloroquine apsPlaquenil mefloquineNew plaquenil dosing guidelines Plaquenil hydroxychloroquine is a good choice for people who have difficulty tolerating newer biologic medications. A generic form of Plaquenil hydroxychloroquine is available. chloroquine is generally safe to use during pregnancy and for children. You can take chloroquine with or without food. Compare Plaquenil vs Chloroquine -. Systematic review of hydroxychloroquine use in pregnant.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Recent studies suggest that hydroxychloroquine Plaquenil is safe for use during pregnancy.3 Nonsteroidal anti-inflammatory drugs NSAIDs such as ibuprofen and aspirin should be avoided during pregnancy unless prescribed by a doctor. Take this medication with a meal or a glass of milk to prevent stomach upset. Common side effects include nausea, loss of appetite, headache, and diarrhea. Plaquenil can cause blurred vision and dizziness. Do not drive or operate heavy machinery until you know how it affects you. Until 1995, nearly all physicians stopped hydroxychloroquine Plaquenil when a patient with lupus erythematosus LE became pregnant because there were no data on whether the drug was safe during pregnancy, said Dr. Piette of Hôpital Pitié-Salpétrière, Paris.