Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil versus hydroxychloroquine Plaquenil side effects antimalarial The need to coadminister these drugs should be done with a careful assessment of risks versus benefits. Chloroquine administration is associated with an increased risk of QT prolongation and TdP. Some quinolones, including ofloxacin, have also been associated with QT prolongation. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use chloroquine phosphate exactly as directed. Do not use more or less of it or use it more often than prescribed by your. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Pros of chloroquine Chloroquine Indications, Side Effects, Warnings -, Chloroquine C18H26ClN3 - PubChem Chloroquine phosphate in myocardial protectionPlaquenil sun allergyChloroquine resistance mechanism of actionHow is hydroxychloroquine madePlaquenil y alcohol Our Aralen chloroquine phosphate Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Side Effects of Aralen Chloroquine, Warnings, Uses. Chloroquine MedlinePlus Drug Information. Chloroquine Mode of Action Science. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat. Education and information regarding choosing a drug to prevent malaria, including a list of all available drugs and reasons for taking or not taking a certain drug. Chloroquine is rapidly and almost completely absorbed from the gastrointestinal tract, and only a small proportion of the administered dose is found in the stools. Approximately 55% of the drug in the plasma is bound to nondiffusible plasma constituents. Excretion of chloroquine is quite slow, but is increased by acidification of the urine.