She otherwise felt well, and reported that her lupus was inactive. She denied any associated chest pain, cough, or fever. Chloroquine cancer clinical trial Plaquenil for pericarditis The risk may also be higher with some doses of Plaquenil hydroxychloroquine, if you use Plaquenil hydroxychloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Call your doctor right away if you have any eyesight changes like blurred or foggy eyesight, trouble focusing or reading, or trouble seeing in dim light. Most cases of shortness of breath are due to heart or lung conditions. Your heart and lungs are involved in transporting oxygen to your tissues and removing carbon dioxide, and problems with either of these processes affect your breathing. Shortness of breath that comes on suddenly called acute has a limited number of causes, including A 30 year old woman with systemic lupus erythematosus SLE was admitted to hospital complaining of shortness of breath, orthopnoea, swelling of ankles, and increased weight over the preceding eight days. She otherwise felt well, and reported that her lupus was inactive. She denied any associated chest pain, cough, or fever. A similar presentation had occurred three months previously, when she. Investigations performed at that time included a complete blood picture, cardiac enzymes, and the measurement of antibodies against double stranded DNA (ds DNA). A similar presentation had occurred three months previously, when she went to another hospital with the same symptoms, associated with a raised temperature (38.4°C). Shortness of breath related to plaquenil Home Treatments for Shortness of Breath, Shortness of breath Causes - Mayo Clinic Retinal exam for plaquenil Symptoms of larynx involvement caused by RA include odynophagia painful swallowing, foreign body sensation, dysphagia difficulty swallowing, sore throat, lump sensation in the throat, change in voice quality e.g. hoarseness, breathiness, vocal fatigue, referred otalgia earache. Hoarseness and Shortness of Breath Is Your Rheumatoid.. Shortness of breath in systemic lupus erythematosus a diagnostic and.. Important Causes of Shortness of Breath - Dyspnea Explained. Hallucinations, seizures, and hearing loss are among the serious side effects of Plaquenil. This eMedTV Web page provides a more in-depth list of potentially dangerous reactions and explains when to report such problems to your doctor. Shortness of breath will quickly escalate if the reaction causes your throat to swell and close off, blocking your air supply. You may also itch, wheeze, and have vomiting and diarrhea. Aug 04, 2016 Although I understand from your post that you had shortness of breath before starting your plaquenil regimen, it sounds as if upper respiratory problems are worse for you since you started taking it. I suggest you ask your doctor whether plaquenil might be related to the breathing difficulties you're having.