Tel.: ( 44) 20 8869 2831; fax: ( 44) 20 8869 2836; e-mail: All cases of falciparum malaria are potentially severe and life threatening, especially when managed inappropriately. A major reason for progression from mild through complicated to severe disease is missed or delayed diagnosis. Chloroquine and arthritis What is chloroquine resistance The usefulness of chloroquine as the first line drug for the treatment of acute simple and complicated malaria has been threatened in many Sub-Saharan African countries by the emergency of P. falciparum resistant to chloroquine. Chloroquine can be prescribed for either prevention or treatment of malaria. This fact sheet provides. information about its use for the prevention of malaria infection associated with travel. Center for Global Health Division of Parasitic Diseases and Malaria. Who can take chloroquine? Chloroquine can be prescribed to adults and children of all ages. For pregnant women diagnosed with uncomplicated malaria caused by chloroquine-resistant P. falciparum infection, women in the second and third trimesters can be treated with artemether-lumfantrine, and for all trimesters, mefloquine or a combination of quinine sulfate and clindamycin is recommended. Quinine treatment should continue for 7 days for infections acquired in Southeast Asia and for 3 days for infections acquired elsewhere; clindamycin treatment should continue for 7 days. The most recent advance in antimalarial chemotherapy has been the use of artemisinin derivatives especially intravenous artesunate, which may well revolutionize the management of severe disease. Once diagnosed, the priority for treatment of complicated and severe disease is the parenteral administration of adequate, safe doses of an appropriate antimalarial, in the setting of the highest possible level of clinical care (i.e. Supportive management of complications such as coma, convulsions, metabolic acidosis, hypoglycaemia, fluid and electrolyte disturbances, renal failure, secondary infections, bleeding disorders and anaemia is also important. Treatment of cerebral malaria chloroquine Malaria Treatment -, Medicines for the Prevention of Malaria While Traveling. Plaquenil sun tanHydroxychloroquine and the fluCan plaquenil cause hivesPlaquenil 200 mg oral tabletAlternatives to plaquenil for rheumatoid arthritis Chemotherapy for cerebral malaria mainly involves the use of quinine a bitter alkaloid extracted from the Cinchona tree bark, in case the patient exhibits chloroquine. Artemisinin, a clinically approved drug, is known to cure fever and parasitemia, faster than chloroquine or quinine. Commonly. Cerebral Malaria Symptoms and Treatment - Health Hearty. CDC - Malaria - Diagnosis & Treatment United States.. TREATMENT OF SEVERE MALARIA - Guidelines for the Treatment of.. Summary. Aralen is the brand name for the generic drug chloroquine, an anti-malaria drug used to treat malaria and amebiasis infection that's spread outside of the intestines. Dosage, drug interactions, and pregnancy and breastfeeding safety information should be reviewed prior to taking this drug. Cerebral malaria – in rare cases, the small blood vessels leading to the brain can become blocked, causing seizures, brain damage and coma The effects of malaria are usually more severe in pregnant women, babies, young children and the elderly. Malaria or parasitemia, or patients who acquired malaria in a geographic area where chloroquine resistance is known to occur should be treated with another form of antimalarial therapy see.