They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Plaquenil teva Plaquenil dosage for lyme disease What is hydroxychloroquin Methotrexate does suppress the immune system, but serious infections with methotrexate are not common. Your rheumatologist will monitor you closely for any side effects associated with methotrexate such as liver test abnormalities, pneumonitis, or infections. Almost all autoimmune diseases require the immune system be suppressed to some degree, because ‘overactivity’ of the immune system is what drives the illness. I can't give you a specific answer here, but I can tell you that I did a lot of research on the subject when I first started plaquenil and I really couldn't find anything definitive that says "plaquenil suppresses the immune system." It does seem to suppress autoimmune activity in lupus - my sister has seen great results from this - but I like to assume that no doctor would prescribe this stuff for people with chronic infections if it was likely to suppress our immune systems. Thomas says he understands people’s concerns about the drug’s potential for toxicity. “But you can’t even compare it to the only other things I have to treat lupus—prednisone, where 100 percent of people get side effects, or immunosuppressive drugs, which suppress the immune system. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Does plaquenil suppress the immune system Do either hydroxychol/Plaquenil put you at risk for greater., Is Plaquenil an immumo-suppressant? - Side effects discontinuing plaquenil Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining. Anyone on Hydroxychloroquine plaquenil - Autoimmune.. Protecting your eyesight when taking Plaquenil Lupus Foundation of.. Cannabis May Suppress Immune System. My gyn oncologist was concerned that the Plaquenil may affect my immune system to ward of the hpv since we all know a good immune system is needed to fight the virus --- He understands the RA pain conundrum I have. It also is used for certain autoimmune conditions, which concerns me. If Plaquenil suppresses the immune system, why are some Lyme drs using it in their protocols? Most Lyme drs have strong opinions about avoiding anything that may lower the immune system. What makes Plaquenil any different? These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives.