Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. How long does hydroxychloroquine take to work Plaquenil and fevers Chloroquine hydroxychloroquine quin Aug 29, 2014 Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as, age of greater than 60 years, daily dose more than 6.5 mg/kg; use of the drug more than 5 years, obesity, preexisting retinal disease and, renal or liver failure. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Most of the medications used for treatment of RA have potential toxicities, though Plaquenil is widely believed not to add significant risk to surgery and to wound healing. The lower the prednisone dose, the better. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and surgery risk Perioperative management of the patient with rheumatoid arthritis, Protecting your eyesight when taking Plaquenil Lupus. What exactly does plaquenil doPlaquenil first dose I just had major spine surgery in November. The surgeon had me check with my rheumy about stopping Plaquenil and I was told to continue it, or just stop it the day of surgery then get right back on, I asked what would happen if I stopped for a week and was told I'd risk going into a flare. Stopping Plaquenil before surgery Lupus Forums at The.. I Have Lupus, My Rheumatologist Has Given Me a Green Light.. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. When patients on immunosuppressive therapies need surgery, the risks of disease flare and compromised postoperative recovery and rehabilitation must be weighed against the risk of increased infections and impaired wound healing. Aug 21, 2014 There are several risks involved with breast reduction surgery. They can involve the following infection, bleeding issues, reaction to anesthetic, uneven breast, nipple problems and nipple numbness. Breast reduction surgery holds many risks.