It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Plaquenil and breast cancer Plaquenil and aps Can i take eyebright with plaquenil Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases. Two plaquenil a day and 2400 mg of ibuprofen a day that's 12 regular dose! and I went into total remission. Of course my stomach is crap now. After 25 years of remission, the RA returned. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Plaquenil dose for arthritis Plaquenil vs. Prednisone Prescription Treatment for., Plaquenil User Reviews for Rheumatoid Arthritis at Plaquenil immune systemRa drug plaquenil Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil hydroxychloroquine sulfate dose, indications.. Hydroxychloroquine dosage recommendations often ignored. 81% were women, and patients had been taking HCQ for an average of just over 6 years, primarily for rheumatoid arthritis or systemic lupus erythematosus. Nearly two-thirds had a high risk for retinal toxicity. Based on the 2011 recommendations from the AAO and ACR, 17% of the patients. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Dosage for rheumatoid arthritis Adult dosage ages 18 years and older Typical starting dosage 400–600 mg per day, given as a single daily dose or in two 2 divided doses.