Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. What is chloroquine made of Plaquenil oral side effects Which drugs or supplements interact with hydroxychloroquine Plaquenil? Administration of hydroxychloroquine with penicillamine Cuprimine, Depen may increase penicillamine levels, increasing the risk of penicillamine side effects. The mechanism is unknown. According to WebMD, in most cases, you don’t need to be worried about drug interactions when taking hydroxychloroquine. It has only a mild effect on the immune system, but you should still tell your doctors what you are taking. Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine interactions Hydroxychloroquine DermNet NZ, RA and Hydroxychloroquine How Effective is it for Rheumatoid Arthritis. Does plaquenil affect gerd Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Plaquenil - Uses, Side Effects, Interactions -. Hydroxychloroquine MedlinePlus Drug Information. Hydroxychloroquine Drug Interactions - Serious Interaction.. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Hydroxychloroquine may interact with other medications Heart drug. Taking digoxin with hydroxychloroquine may increase the levels of digoxin in your body. Insulin and other diabetes drugs. Hydroxychloroquine and diabetes drugs all decrease your blood. Drugs that affect heart rhythm. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.