Intermittent preventive therapy chloroquine

Discussion in 'Chloroquine 250' started by rzninet, 04-Mar-2020.

  1. nicolaevich Moderator

    Intermittent preventive therapy chloroquine


    Intermittent preventive treatment of malaria in pregnancy is a full therapeutic course of antimalarial medicine given to pregnant women at routine antenatal care visits, regardless of whether the recipient is infected with malaria. IPTp reduces maternal malaria episodes, maternal and fetal anaemia, placental parasitaemia, low birth weight, and neonatal mortality.

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    Abstract. Background. Malaria during pregnancy contributes to maternal anemia and low birth weight. In East Africa, several studies have demonstrated that intermittent preventive treatment IPT with sulfadoxine-pyrimethamine SP is more efficacious than weekly chloroquine CQ chemoprophylaxis in preventing these adverse consequences. Falciparum malaria is an important cause of maternal, perinatal and neonatal morbidity in high transmission settings in Sub-Saharan Africa. Intermittent preventive treatment with sulphadoxine-pyrimethamine SP-IPT has proven efficacious in reducing the burden of pregnancy-associated malaria but increasing levels of parasite resistance mean that the benefits of national SP-IPT programmes may. When comparing chloroquine and sulfadoxine-pyrimethamine as intermittent therapy for the treatment of malaria in pregnant women — in a setting of high resistance to sulfadoxine-pyrimethamine.

    Adults who have survived repeated malaria infections throughout their lifetimes may become partially immune to severe or fatal malaria. The TIPTOP project is an innovative, community-based approach that aims to dramatically increase the number of pregnant women in malaria-affected countries in sub-Saharan Africa receiving antimalarial treatment.

    Intermittent preventive therapy chloroquine

    Chloroquine Dosage Guide with Precautions -, Intermittent preventive treatment for malaria in pregnancy in.

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  4. Intermittent preventive treatment with an antimalarial drug during pregnancy such as sulphadoxine-pyrimethamine SP is a cost-effective means of preventing malaria in pregnancy. Several studies have demonstrated its efficacy in causing a decline in placental infection, anemia, and low birth weight babies, 2.

    • Utilization of Intermittent Preventive Treatment of..
    • Chloroquine as prophylaxis may offer pregnant women..
    • Drivers of intermittent preventive treatment of malaria..

    In West Africa, treatment for the prevention of malaria during pregnancy has recently changed from chloroquine CQ prophylaxis to intermittent preventive treatment IPTp. We assessed the benefits of IPTp with respect to those of CQ, using a before-after study. Methods. Women allocated intermittent preventive treatment with chloroquine received two cycles of chloroquine at least 4 weeks apart during pregnancy, with a cycle consisting of 600 mg on day 1, 600 mg on day 2, and 300 mg on day 3. Intermittent preventive treatment is the prescheduled administration of antimalarial drugs to at-risk patients in endemic areas. This approach, which is recommended for pregnant women, is being evaluated in children. Sulfadoxine–pyrimethamine plus amodiaquine recently proved to be more protective than artemisinin-containing regimens. Therefore, the use of artemisinin derivatives could.

     
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