Please review the following URL and make sure that it is spelled correctly. Requested URL: /drugsatfda_docs/label/2017/009768s... Hydroxychloroquine used rheumatoid arthritis Plaquenil and infection risk Chloroquine is an antimalarial agent also used as standard treatment for a variety of rheumatologic and dermatologic disorders. 1,2 Myopathy and, to a lesser extent, neuropathy are well-documented complications of therapy with chloroquine and other antimalarial agents. 1,3 Chloroquine typically produces a vacuolar myopathy 1,2 characterized by progressive proximal weakness that resolves. Similar inclusions in perhexiline & chloroquine. Arsenic inorganic Toxicity Sources Suicidal, Homicidal, Occupational, Environmental. Neuropathy development. The latter is related to drug accumulation in melanin-rich tissues. 15,16 Prolonged treatment with chloroquine also can cause toxic myopathy, cardiopathy, and peripheral neuropathy and neuropsychiatric disturbances; all of these reactions improve if the drug is discontinued promptly. 17,18 Both chloroquine and hydroxychloroquine should be used. Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Chloroquine neuropathy Chloroquine - an overview ScienceDirect Topics, Toxic neuropathies Osteoarthritis joint nodules hydroxychloroquineHydroxychloroquine intracellular ph Plaquenil and small fiber neuropathy. I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. All my issues were resolved over a years time on low doses. I believe my problems started with side effects of a statin, which I stopped taking during my Plaquenil treatment but resumed after symptoms were resolved. Plaquenil and small fiber neuropathy - NeuroTalk Support.. Effectiveness of Chloroquine and Hydroxychloroquine in Treating.. Chloroquine retinopathy - Wikipedia. Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease Lupus is a broad term for several autoimmune disorders that weaken the body’s immune system by producing antibodies that attack healthy cells, tissues and organs. We present a case of neuropathy and myopathy in a woman treated chronically with hydroxychloroquine and recently added colchicine. Both agents were felt to have a role in her progressive decline, with hydroxychloroquine likely inducing a mild myopathy over the previous 12 months.