RA is diagnosed though several different tests including blood tests, specifically a reading of the rheumatoid factor in your blood sample. Your body contains antibodies, consisting of a type of protein found in your blood and other body fluids. Discontinuing plaquenil now have muscle spasms Plaquenil retinopathy autofluorescence Due to the high risk of flare in systemic lupus erythematosus when discontinuing this medication, continued Plaquenil use is advised in these patients during pregnancy. Small amounts of hydroxychloroquine can be found in breastmilk, but international experts indicate this medication is acceptable while breastfeeding. MECHANISM OF ACTION According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with arthritis. It can also reduce the incidence of joint damage. I am another one with a diagnosis of UCTD. My symptoms most resemble lupus, but positive ANA is the only specifically associated test that is consistantly positive, other than off and on elevations in Sed rate, CRP and liver enzymes. I had one very mildly positive rheumatoid factor. I've been on Plaquenil for 3 years. Every antibody is unique and specializes in defending the body against one specific antigen. They are part of your immune system and their primary function is to recognize and deal with substances in the body that are foreign. When rheunatoid factor elevates while on plaquenil Plaquenil rheumatoidarthritis, RA and Hydroxychloroquine How Effective is it for. Chloroquine hydrochloric acidHydroxychloroquine plaquenil reviews Plaquenil hydroxychloroquine "Hi, I was taking the generic form of plaquenil for over 10 years for rheumatoid arthritis. It took a few weeks to see it work but what a change for the better. Less painful joints and fatigue. Hydroxychloroquine User Reviews for Rheumatoid Arthritis at. Plaquenil -. Rheumatoid Arthritis & Elevated Liver Enzymes Healthfully. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Hydroxychloroquine oral tablet is used for short-term treatment of malaria, but it may be used for long-term treatment of lupus or rheumatoid arthritis. Hydroxychloroquine comes with risks if you.