Please review the following URL and make sure that it is spelled correctly. Hi everybody, I was wondering if Plaquenil's primary mode of action was to suppress the immune system? Plaquenil use and weight Hydroxychloroquine not working what next Medication reaction to plaquenil Chloroquine phosphate show up on drug test Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. My rheumy has saidand everything I've read on Plaquenil that Plaquenil NEEDS that amount of time to build in your system before it stats to have beneficial effects. Answer Plaquenil, or hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, sys- temic lupus erythematosus SLE and other inflammatory and autoimmune diseases. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. 1 month ago and prior to taking it I rarely ever got sick with colds,flu etc. I am asking this question, because I started this med approx. Does plaquenil lower my immune system Weakened immune system? DailyStrength, Reasonably Well Plaquenil FAQ Side effects of hydroxychloroquine sulfate 200 mg tabletsPlaquenil maculopathy treatment Jun 13, 2019 Plaquenil lowers your immune system’s ability to cause inflammation. This can help control symptoms like rashes, skin and mouth sores and joint pain. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time. What Is Plaquenil? - American Academy of Ophthalmology. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil and lowered immune system - Sjogren's World. All work by suppressing the immune system. If he wants this type of drug he can try to balance control of his autoimmune disease with the risk of infection. What I mean is He might want to consider taking a lower dose of Plaquenil. This won't suppress his immune system quite as much but it also won't completely control his Sjogrens. Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining. Overall, most serious fungal infections are rare, but they do happen. They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections.