If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female. Chloroquine dose medscape Hydroxychloroquine lyme disease The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. The biggest difference between the. Weight-Based Dosing In Adults And Pediatric Patients 6.5 mg/kg 5 mg/kg base, not to exceed 400 mg 310 mg base, once weekly on the same day of the week starting 2 weeks prior to exposure, and continued for 4 weeks after leaving the endemic area. Dec 30, 2015 SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. Weight based dosing plaquenil Plaquenil Risk Calculators, Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Does hydroxychloroquine make you bone painStopping plaquenil during pregnancyPlaquenil 200 mg prospectHydroxychloroquine azithropine combination Weight-based dosing Dose is based on body weight and must be determined by your doctor. At first, 6.5 mg per kilogram kg of body weight, not to exceed 400 mg, once weekly on the same day of the week starting 2 weeks before traveling to an area where malaria occurs, and continued for 4 weeks after leaving the area. What is Plaquenil? - GoodRx. ACR Actual-weight hydroxychloroquine dosing works in SLE, up.. Adherence to Weight-Based Dosing Guidelines in Patients.. Clinical dosing of Plaquenil requires a negotiation between the patient’s rheumatologist and their eye care physician and is based, in part, on an individual patient’s weight, as well as risk factors for Plaquenil toxicity. It’s a careful balance that can require a deft hand and a little bit of forecasting. There were no differences in hydroxychloroquine levels when both height and ideal body weight were compared across the different blood concentrations. This suggests that we are correctly dosing patients based on actual rather than ideal body weight not exceeding a dose of 400 mg per day and indicated that dosing based on height is unnecessary. The current American Academy of Ophthalmology AAO guidelines, published in 2016, recommend a maximum daily hydroxychloroquine dose of ≤5.0 mg/kg of real weight. These guidelines were established to minimize the likelihood of permanent vision loss related to hydroxychloroquine retinopathy.