Drug of choice for chloroquine resistant malaria

Discussion in 'Canadian Pharcharmy' started by boss-on, 10-Mar-2020.

  1. zeta New Member

    Drug of choice for chloroquine resistant malaria


    According to legend it was first brought to Europe by a Countess who had been treated with it in Peru in the 1600s. In 1820, two French chemists isolated quinine from the cinchona bark and quinine became a treatment of reference for intermittent fever throughout the world. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance.

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    Blood schizonticides These drugs act on the blood forms of the parasite and thereby terminate clinical attacks of malaria. These are the most important drugs in anti malarial chemotherapy. These include chloroquine, quinine, mefloquine, halofantrine, pyrimethamine, sulfadoxine, sulfones, tetracyclines etc. Insulin and other antidiabetic drugs As Chloroquine may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or other antidiabetic drugs may be required. Chloroquine is the drug of choice in the few malaria-endemic areas free of CRPf. Combining chloroquine and proguanil is an option for CRPf when other first-line antimalarials are contraindicated. Combining chloroquine and proguanil is an option for CRPf when other first-line antimalarials are contraindicated.

    These compounds belonged to a new class of antimalarials, the four-amino quinolines. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin (chloroquine) and Sontochin (3-methyl-chloroquine).

    Drug of choice for chloroquine resistant malaria

    Anti-malaria, potential coronavirus drug chloroquine can., Chloroquine - FDA prescribing information, side effects and uses

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  4. The risk of acquiring chloroquine resistant P. falciparum malaria CRPF is another consideration. Any previous allergic or other reaction to the antimalarial drug of choice and the accessibility of medical care during travel must also be determined.

    • Malaria Prophylaxis – Malaria Site.
    • Chloroquine - an overview ScienceDirect Topics.
    • Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health..

    Atovaquone-Proguanil FDA-approved in 2000, atovaquone-proguanil Malarone is a combination drug that is used for the prevention and treatment of uncomplicated chloroquine-resistant P. falciparum malaria. MORE Inside the frantic race to find a drug to fight coronavirus Chloroquine, or hydroxychloroquine, has been used to treat malaria since 1944. It can be given before exposure to malaria to prevent infection, and it can also be given as treatment afterward. Malaria is a disease that is caused by a parasite, unlike COVID-19. For P. falciparum infections acquired in areas without chloroquine-resistant strains, which include Central America west of the Panama Canal, Haiti, and the Dominican Republic, patients can be treated with oral chloroquine. A chloroquine dose of 600 mg base = 1,000 mg salt should be given initially, followed by 300 mg base = 500 mg salt at 6, 24, and 48 hours after the initial dose for a total chloroquine dose of 1,500 mg base =2,500 mg salt.

     
  5. Pavlo123 Guest

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  7. Toy Moderator

    Coronavirus Update Access to Hydroxychloroquine. The Lupus Foundation of America is aware of the potential use of hydroxychloroquine Plaquenil and chloroquine Aralen for the treatment of coronavirus COVID-19. This means that these drugs may be in high demand in the coming weeks. We are actively working with our medical and scientific.

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