Estrogen use should be discontinued unless its need outweighs its adverse effects on porphyrin metabolism. After achievement of remission, estrogen therapies may be cautiously reinstituted; however, the duration of remissions may be shortened. Plaquenil 200 mg wikipedia Anti-malarial medicine for chloroquine resistant malaira What is chloroquine made up of Low-Dose Hydroxychloroquine Is as Effective as Phlebotomy in Treatment of Patients With Porphyria Cutanea Tarda Ashwani K. Singal, Csilla Kormos-Hallberg, Chul Lee, V-M Ramanujam, James J. Grady, Daniel H. Freeman, Karl Anderson Usual Adult Dose for Rheumatoid Arthritis. -Initial dose 400 to 600 mg 310 to 465 mg base orally once a day to optimum response usually 4 to 12 weeks -Maintenance dose 200 to 400 mg 155 to 310 mg base orally once a day Dose adjustment The dose may need to be reduced temporarily if adverse side effects occur; Low-dose hydroxychloroquine or chloroquine. These drugs are recommended for patients in whom phlebotomy is contraindicated, difficult, or poorly tolerated. Singal AK, Kormos-Hallberg C, Lee C, et al. Low-dose hydroxychloroquine is as effective as phlebotomy in treatment of patients with porphyria cutanea tarda. If symptoms recur, re-treatment can restore remissions. Remissions may last from several months to many years. Low-dose hydroxychloroquine role in porphyria Porphyria Cutanea Tarda Treatment & Management Medical Care, Surgical., Hydroxychloroquine Dosage Guide with Precautions - What is toxic dose of plaquenil Porphyria Cutanea Tarda and Polymorphous Light Eruptions. Has been used in treatment of porphyria cutanea tarda†. 114 116 117 See Patients with Psoriasis or Porphyria under Cautions. Has been effective in some cases when used in the treatment of polymorphous light eruptions†. Hydroxychloroquine Sulfate Dosage and Administration Administration Hydroxychloroquine Sulfate Monograph for Professionals -. Porphyria cutanea tarda - Approach BMJ Best Practice. PDF Low-Dose Hydroxychloroquine Is as Effective as Phlebotomy in.. Porphyria cutanea tarda PCT is an iron-related disorder that responds to treatment by phlebotomy or low-dose hydroxychloroquine, but comparative data on these treatments are limited. The hypothesis is that hydroxychloroquine is noninferior to phlebotomy in terms of time to remission. Singal AK, Kormos-Hallberg C, Lee C, Sadagoparamanujam VM, Grady JJ, Freeman DH Jr. Low-dose hydroxychloroquine is as effective as phlebotomy in treatment of patients with porphyria cutanea tarda. Read "Low-Dose Hydroxychloroquine Is as Effective as Phlebotomy in Treatment of Patients With Porphyria Cutanea Tarda, Clinical Gastroenterology and Hepatology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.