Note the presence of a confluent, erythematous eruption that is not only in a photodistribution but is now on the breasts and upper abdomen. Plaquenil is the brand name for the prescription drug hydroxychloroquine. 200 20 000 chloroquine Tylenol and plaquenil Does plaquenil affect my immune system Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. View detailed reports from patients taking Hydroxychloroquine Sulfate who experienced rash. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. I broke out with a rash after being on it for a week. I was also on a mild muscle relaxer for about 3 weeks prior to plaquenil. I got off both then started back on plaquenil. No rash so I assumed it was the other med even though I was on it longer and before the plaquenil. Did not resume the other meds. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil and skin rashes Taking Plaquenil for Rheumatoid Arthritis, Hydroxychloroquine Sulfate Rash Reports - DrugInformer The avgerage dosage a person takes of plaquenilChloroquine dosage adult An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis. Objective To determine if adverse cutaneous eruptions due to hydroxychloroquine are more common in patients with dermatomyositis than in those with cutaneous lupus erythematosus. Adverse Cutaneous Reactions to Hydroxychloroquine Are More.. Plaquenil rash I just started taking. - Sticky Blood-Hugh.. Common and Rare Side Effects for Plaquenil Oral. Do not use Plaquenil without telling your doctor if you are breast-feeding. Our blog on Lupus and Pregnancy has much more valuable information on this topic. Back to top. We hope that this blog has been helpful in answering some of your questions about Plaquenil and other antimalarial drugs used to treat lupus. Less common adverse effects of Plaquenil are drug-induced skin rashes. These rashes may consist of many small red bumps or bright red skin covering most of the body. The severity of the rash indicates to the clinician whether the drug needs to be stopped and even whether it will be tried again. Skin conditions associated with lupus are fairly significant and a major marker of the disease. Of the eleven criteria set by the American College of Rheumatology for a diagnosis of lupus, four are skin-related. These include Malar rash - “butterfly rash” that appears on the cheeks; Discoid rash - red patches on the skin that can lead to.