Side effects of a number of medications also mimic some signs and symptoms of Sjogren's syndrome. Tests can help rule out other conditions and help pinpoint a diagnosis of Sjogren's syndrome. Plaquenil 500 mg Plaquenil and type 1 diabetes What is the drug hydroxychloroquine used for Plaquenil is taken for treating Sjogren's Syndrome. 4,677 patients conversations about taking Plaquenil for Sjogren's Syndrome, rating Plaquenil 3.165344186273461 out of 5 for helping in treatment of Sjogren's Syndrome. Other potential side effects include but are not limited to nausea, changes in mood, muscle weakness, skin pigmentation and anemia. While the drug may be used during pregnancy, the potential benefits and risks should be discussed with your doctor. In summary, if you have Sjögren’s, hydroxychloroquine may be an option to help your symptoms. Side effects of methotrexate are varied. It is a drug that must be monitored closely by a patient’s physician. Common complaints consist of mouth sores, stomach upset, loss of appetite, fatigue or headache. Some patients notice mild hair loss, more of a thinning, usually more noticeable to the patient than to friends or family. A small piece of filter paper is placed under your lower eyelid to measure your tear production. Your doctor can measure the dryness of your eyes with a test called a Schirmer tear test. Plaquenil dosage sjogren's syndrome Treatment/Plaquenil -, Ask the Expert Plaquenil and Sjögren’s - info. Chloroquine reduce cell viabilityDoes chloroquine affect birth controlChloroquine mode of mechanism action Reviews and ratings for hydroxychloroquine when used in the treatment of sjogren's syndrome. 45 reviews submitted. User Reviews for Hydroxychloroquine to treat Sjogren's Syndrome. Also known as Plaquenil. The other immune drugs have scary side effects almost worth waiting for a flare and dealing with steroids then the side effects of. Hydroxychloroquine User Reviews for Sjogren's Syndrome at.. Methotrexate and its benefit for Sjögren’s patients. Leflunomide-Hydroxychloroquine Combo Shows Potential for.. If I fight it too much, I have a flare. It takes like 4 months for the Plaquenil to build up and the sickness usually goes away, until you have to increase the dose. It took me 10 years to learn to listen to my body. I was afraid if I didn't fight I would let Sjogrens and Lupus win. I decided to compromise. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva. Although you can develop Sjogren's syndrome at any age, most people are older than 40 at the time of diagnosis. The condition is much more common in women. Sjogren's Syndrome Support Group. Sjogren's syndrome is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. It also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases.