A, At the start of hydroxychloroquine sulfate treatment. B, Two years after starting treatment, a right paracentral scotoma appeared. What conditions does plaquenil treat Can hydroxychloroquine cause low white blood cell count Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Jan 01, 2020 The molecular weight of hydroxychloroquine sulfate is 433.95, and molecular formula is C 18 H 26 ClN 3 O. H 2 SO 4. Plaquenil hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Inactive Ingredients Dibasic calcium phosphate USP. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Morand EFMc Cloud PILittlejohn GO Continuation of long term treatment with hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis. C, Three years after cessation of treatment, the scotoma regressed. Plaquenil visual field red stimulus Value of Red Targets and Pattern Deviation Plots in Visual., Plaquenil - FDA prescribing information, side effects and uses Hydroxychloroquine and alcohol use Part 1 in a three part series that attempts to clarify all the questions surrounding visual fields. This part focuses on obtaining visual fields. It’s suggested that patients taking Plaquenil get 10-2 fields done every few years to watch for maculopathy. It’s a longer test that uses a red stimulus, so be sure to select the right setting Dots, Squiggles, and Triangles, Oh My! A Visual Field.. Recommendations on Screening for Chloroquine and.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Five consecutive 10-2 visual fields VFs with a white target. Notes VFs of a patient taking hydroxychloroquine at toxic doses who developed retinopathy. An incomplete annular scotoma in the zone from 2 to 8 degrees from fixation developed in the third VF. This scotoma was reproducible and enlarged from 2011 to 2012. Visual Fields Early toxicity can cause bilateral relative paracentral scotomas. 4 Defects can be present BEFORE definitive signs are seen on fundus examination. Some experts suggest using a red stimulus or blue-yellow perimetry for early detection of retinopathy. 5 The AAO recommends that all patients beginning hydroxychloroquine therapy have a baseline evaluation, including a complete dilated examination and visual field test Amsler grid or Humphrey 10-2 perimetry. Other testing, such as color vision and fundus photography, is optional.