The patient experienced a ventricular tachycardia leading to cardiac arrest and was found to have a prolonged QT interval. Although citalopram is eliminated more slowly in patients with mild to moderate renal impairment a dose adjustment is not necessary. However, no information is available on treatment of patients with severely reduced renal function and prescribers are advised to use caution. Hydroxy-chloroquine 200 mg without prescription Plaquenil fish oil Mar 10, 2016 In case of TdP arrhythmia QT interval prolongation can be used as a relatively safe indicator of PD drug interaction result, though a number of drug combinations possibly implicated in QT prolongation is practically infinite and it is infeasible to comprehensively assess all of them during the drug development process and clinical trials. Cardiac Effects, including Cardiomyopathy and QT prolongation Postmarketing cases of life-threatening and fatal cardiomyopathy have been reported with use of Plaquenil as well as with use of chloroquine. Patients may present with atrioventricular block, pulmonary hypertension, sick sinus syndrome or with cardiac complications. Citalopram/QT Prolonging Agents Interactions. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. QT prolongation is a measure of delayed ventricular repolarisation, which can cause Torsades de Pointes, ventricular tachycardia, and sudden death. In elderly patients, patients with reduced hepatic function, patients who are CYP2C19 poor metabolisers, and patients taking CYPC19 inhibitors (eg, cimetidine and omeprazole), the maximum dose should not exceed 20 mg a day because these factors lead to increased blood levels of citalopram. Plaquenil and citalopram qt prolongation Citalopram and escitalopram QT interval prolongation - GOV. UK, Plaquenil - FDA prescribing information, side effects and uses Weight loss with plaquenilFolic acid and hydroxychloroquineHydroxychloroquine interactionsCheap aralen malariaDrug information about chloroquine The citalopram drug label was revised on August 12, 2011 and again on March 27, 2012, to include new warnings about the potential for QT interval prolongation and Torsade de Pointes, as well as new drug dosage and usage recommendations. Revised recommendations for Celexa. Interactions between Levaquin Oral and qt-prolonging-agents.. QTc Prolongation With Antidepressants and Antipsychotics. Hydroxychloroquine/QT Prolonging Agents Interactions. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. Plaquenil - Store at controlled room temperature between 68 and 77 degrees F. Citalopram causes dose-dependent QT interval prolongation. According to the manufacturer, concurrent use of citalopram with other drugs that prolong the QT interval is not recommended. QT prolongation and torsade de pointes TdP have been reported in. Nov 08, 2011 The maximum dose of citalopram is now 40mg daily. In the elderly and in patients with reduced hepatic function the maximum dose is lowered to 20mg daily. Citalopram is contraindicated in patients with known QT interval prolongation or congenital long QT syndrome.