The pharmacist said there wont be any danger just stopping it. Has anyone gone off the plaquenil and what happened? I was put on Plaquenil for RA as I was being dx for lupus. My rhuemy wants me to stop every time I have an infection. Best of luck, Creekbank My mom said she read that plaquenil is mainly used for the discoid lupus and people with the joint pain. Right now my hips are the only thing that is really bothering me my knees are now starting to act up..... Chloroquine weekly Chloroquine p53 lysosome I was put on Plaquenil for RA as I was being dx for lupus. I am very mild. My rhuemy wants me to stop every time I have an infection. When it is gone she said I can resume at my own pace. Take into consideration I only take Plaquenil and ibuprofen 800mg. My symptoms came back after two weeks of being off it. Hi. I have been taking Plaquenil, 200mgs 2x a day for about 2 years. I have not tested positive for Lupus, RA or SjS but it took over 13 years before my sister finally tested positive for Lupus & RA. You can still have Lupus/RA & not be positive. Anti-malarial drugs may be given in combination with prednisone to reduce the amount of steroid needed to control lupus symptoms and thus to alleviate some of the side effects of the steroid. In addition, since it usually takes about 1-3 months for your anti-malarial medications to fully take effect, you may be given a steroid medication to act as a bridging medication and alleviate your symptoms during this interim. There is no taper needed or withdrawal, but if it has been helping you, you may have increased symptoms by the time you go for your next appointment. If so, you would likely be able to get a prescription from that doctor for one month's supply to tide you over. I have only taken it once, so I am not sure what the results will be. I stopped mine and went into a life threatening flare - I would call your PCP to get a refill You may be fine or not- depends on if your illness has been lurking in the background waiting for an opportunity to launch an attack Louters, I went to see a new rheum and he took me off the Plaquenil to see what symptoms would show. I agree with poobie and would call your pcp to get a refill if possible. Stop taking plaquenil and prednisone for my lupus Prednisone and Plaquenil DailyStrength, Hydroxychloroquine plaquenil withdrawl? - LUPUS UK Does plaquenil compromise the immune systemPlaquenil for pregnancy loss What is the correct way to discontinue use of plaquenil? Asked 12 Nov. Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. my eye sight changes every time i go for glasses my hair fell out not sure if its due to the lupus itself or the meds. but when i stop taking the drug the. What is the correct way to discontinue use of plaquenil?. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Plaquenil and corona lupus. My Mom's Dr's wan'ts her to take both Prednisone and Plaquenil together. I have not heard of this being done. I was wondering if anyone has done both med's at the same time and the effects. Mom has Lupus like me, but she was diagnosed when she was 40 yrs old and now she is 58. She has and enlarged heart, diabetes, had a stroke, and failing kidneys. Prednisone a corticosteroid and methotrexate are best taken at specific times of day. “I tell people to take prednisone first thing in the morning, with something in their stomach,” says Mary Anne Dooley, MD, MPH, associate professor of rheumatology and immunology at the University of North Carolina’s Thurston Arthritis Research Center. Patients who take prednisone may find this long list of side-effects overwhelming. It is important to remember that no physician ever prescribes prednisone unless it is needed, that prednisone is often the most important tool in the fight against lupus and that the physician always tries to keep any side-effects to a minimum.