Additionally, another exception occurred while executing the custom error page for the first exception. The resource you are looking for (or one of its dependencies) could have been removed, had its name changed, or is temporarily unavailable. Difference between hydroxychloroquine and methotrexate Using chloroquine to treat ich Hydroxychloroquine class action lawsuit Chloroquine kills sporozoites Nine years after discontinuing medical therapy, the patient had new scotomas, difficulty reading and progression of bull’s-eye maculopathy. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. Went back this year, and I’ve lost 40% of my peripheral vision, and am showing “quite severe” plaquenil related toxicity of the retina. Wtf. The eye doctor said it normally takes at least 10 years for people to start having problems with their eyes while on plaquenil, and when they do it comes on a lot slower than this. If you stopped taking Plaquenil, how long did it take for side effects to subside? This will put you to the top of the list for more replies. Please review the following URL and make sure that it is spelled correctly. 5 years for plaquenil to leave eye Plaquenil - how long for side effects to subside?, New Plaquenil Guidelines Drug interactions with hydroxychloroquineSide effects of plaquenil on the eyesCan you drink alcohol while taking hydroxychloroquineMichael marmor plaquenil dec 2015Chloroquine schedule The risk of a toxicity sharply increases after 5 years, with majority of cases of retinotoxicity occurring in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day 200 bid. Plaquenil Risk Calculators. Plaquenil and eye problems? lupus. Plaquenil and Intraocular pressure increased - eHealthMe. In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more likely to occur in individuals taking high doses for many years, individuals 60 years or older, or those with significant kidney disease. At the recommended dose, development of visual problems due to the medication is rare. Eye Exam and Testing for Plaquenil. For the first 5 years annual screening is appropriate. In addition to the previous discussion of a thorough complete eye exam with best corrected vision, central visual field, color vision, and dilated retinal exam, other tests include multifocal ERG, spectral domain OCT, and autofluoresence of the macula. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so.